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|1. (WO2017035767) METHOD AND SYSTEM FOR GENETIC MANIPULATION OF SOUND-SENSITIVE ION CHANNELS|
|Applicants:||SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
|Title:||METHOD AND SYSTEM FOR GENETIC MANIPULATION OF SOUND-SENSITIVE ION CHANNELS|
A method and system for genetic manipulation of sound-sensitive ion channels. The method comprises: acquiring a sound wave (101); focusing the sound wave on endogenous mechanosensitive ion channels of nerve cells to be stimulated, opening the endogenous mechanosensitive ion channels, and/or focusing the sound wave on exogenous mechanosensitive ion channels of the nerve cells to be stimulated, and opening the exogenous mechanosensitive ion channels, to change a membrane potential of the nerve cells (102). This solution implements noninvasive, accurate, and selectively-specific nerve operation and regulation by means of a sound wave.