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1. (WO2017035500) PATIENT-SPECIFIC TISSUE ENGINEERED VASCULAR GRAFT UTILIZING ELECTROSPINNING
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Pub. No.: WO/2017/035500 International Application No.: PCT/US2016/049080
Publication Date: 02.03.2017 International Filing Date: 26.08.2016
IPC:
A61F 2/06 (2013.01) ,A61F 2/82 (2013.01) ,A61F 2/90 (2013.01) ,A61L 27/00 (2006.01) ,B29C 67/00 (2017.01) ,D01D 5/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
04
Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
06
Blood vessels
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
82
Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
82
Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
86
Stents in a form characterised by wire-like elements; Stents in a form characterised by a net-like or mesh-like structure
90
characterised by a net-like or mesh-like structure
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
B PERFORMING OPERATIONS; TRANSPORTING
29
WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
C
SHAPING OR JOINING OF PLASTICS; SHAPING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL; AFTER- TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
67
Shaping techniques not covered by groups B29C39/-B29C65/93
D TEXTILES; PAPER
01
NATURAL OR ARTIFICIAL THREADS OR FIBRES; SPINNING
D
MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES, OR RIBBONS
5
Formation of filaments, threads, or the like
Applicants:
CHILDEN'S NATIONAL MEDICAL CENTER [US/US]; 111 Michigan Avenue, NW Washington, DC 20010-2970, US
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL [US/US]; 700 Children's Drive Columbusm, OH 43205, US
NANOFIBER SOLUTIONS [US/US]; 1275 Kinnear Road Columbus, OH 43201, US
Inventors:
KRIEGER, Axel; US
HIBINO, Narutoshi; US
JOHNSON, Jed; US
OPFERMANN, Justin; US
COCHENOUR, Carolyn; US
BREUER, Christopher K.; US
Agent:
TARCU, Robert; US
LOVE, James; US
Priority Data:
62/209,99026.08.2015US
Title (EN) PATIENT-SPECIFIC TISSUE ENGINEERED VASCULAR GRAFT UTILIZING ELECTROSPINNING
(FR) GREFFON VASCULAIRE CONSTRUIT PAR GÉNIE TISSULAIRE DE TISSU SPÉCIFIQUE AU PATIENT PAR ÉLECTROFILAGE
Abstract:
(EN) A method for generating a electro spun fiber medical implant including determining dimensions of a portion of anatomy of a patient corresponding to the electro spun fiber medical implant via medical imaging, generating a model of the portion of the anatomy based on the dimensions, the model including one or more solid areas and one or more void areas encompassed within the one or more solid areas, inverting the model to generate a mandrel model, the mandrel model generated based on the one or more void areas, generating the mandrel based on the mandrel model, the mandrel including at least one electrically conductive material therein, and applying an electrospinning process to the mandrel to generate the electro spun fiber medical implant which circumscribes the mandrel, wherein the mandrel is removable from within the electro spun fiber medical implant after a disassembly process.
(FR) La présente invention concerne un procédé pour générer un implant médical de type fibre électrofilée comprenant la détermination, par imagerie médicale, des dimensions d'une partie de l'anatomie d'un patient correspondant à l'implant médical de type fibre électrofilée, la génération d'un modèle de la partie de l'anatomie sur la base des dimensions, le modèle comprenant une ou plusieurs zones solides et une ou plusieurs zones vides incluses à l'intérieur de la ou des zones solides, l'inversion du modèle pour générer un modèle de mandrin, le modèle de mandrin étant généré sur la base de la ou des zones vides, la génération du mandrin sur la base du modèle de mandrin, le mandrin comprenant au moins un matériau électroconducteur, et l'application d'un processus d'électrofilage au mandrin pour produire l'implant médical de type fibre électrofilée qui circonscrit le mandrin, le mandrin étant amovible à partir de l'intérieur de l'implant médical de type fibre électrofilée après un processus de démontage.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)