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1. (WO2017035472) CHIRAL CONVERSION OF AMYLOID PROTEINS ASSOCIATED WITH DISEASES

Pub. No.:    WO/2017/035472    International Application No.:    PCT/US2016/048993
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 27 01:59:59 CEST 2016
IPC: A61K 38/00
A61P 25/28
C07K 14/435
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: RASKATOV, Jevgenij A.
Title: CHIRAL CONVERSION OF AMYLOID PROTEINS ASSOCIATED WITH DISEASES
Abstract:
Provided are pharmaceutical formulations that include an amyloid polypeptide including at least one D-amino acid, and a pharmaceutically acceptable carrier. Also provided are kits that include the pharmaceutical formulations. Methods that employ the pharmaceutical compositions are also provided, as are methods for reducing solubility of an all-L amyloid polypeptide in a fluid, methods for characterizing an amyloid polypeptide of interest, and methods for removing an amyloid polypeptide from a bodily fluid.