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1. (WO2017035116) METHODS AND COMPOSITIONS RELATING TO THE DIAGNOSIS AND TREATMENT OF CANCER

Pub. No.:    WO/2017/035116    International Application No.:    PCT/US2016/048133
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Wed Aug 24 01:59:59 CEST 2016
IPC: A61P 35/00
A61P 35/02
C12N 15/113
C12Q 1/68
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventors: GUJRAL, Taran
KIRSCHNER, Marc W.
Title: METHODS AND COMPOSITIONS RELATING TO THE DIAGNOSIS AND TREATMENT OF CANCER
Abstract:
Described herein are methods and compositions relating to the treatment of cancer, e.g., methods which account for a subject's Hippo pathway activity/mutational status or which relate to combination treatments that influence the subject's Hippo pathway activity in order to enhance the effectiveness of chemotherapeutics.