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1. (WO2017035107) SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS

Pub. No.:    WO/2017/035107    International Application No.:    PCT/US2016/048110
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Wed Aug 24 01:59:59 CEST 2016
IPC: A01N 25/30
A01N 37/46
A01N 59/12
A01N 59/16
A61L 27/00
A61L 29/00
A61L 31/16
A61K 31/00
A61K 33/18
A61K 33/38
A01N 37/02
Applicants: SMITH & NEPHEW, INC.
Inventors: JOVANOVIC, Aleksa
SHI, Lei
ROCHE, Eric
RENICK, Paul
Title: SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
Abstract:
The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.