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1. (WO2017034972) NOVEL METHODS OF EVALUATING PERFORMANCE OF AN ATMOSPHERIC PRESSURE IONIZATION SYSTEM

Pub. No.:    WO/2017/034972    International Application No.:    PCT/US2016/047749
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 20 01:59:59 CEST 2016
IPC: H01J 49/00
B01D 59/44
H01J 49/30
H01J 49/40
Applicants: PHARMACADENCE ANALYTICAL SERVICES, LLC
Inventors: KING, III, Richard C.
METZLER, IV, William J.
Title: NOVEL METHODS OF EVALUATING PERFORMANCE OF AN ATMOSPHERIC PRESSURE IONIZATION SYSTEM
Abstract:
The present invention comprises novel methods of continuously monitoring the performance of an atmospheric pressure ionization (API) system. The methods of the invention allow for improved quality monitoring of the processes that leads to the formation of ions at atmospheric pressure. The methods of the invention further allow for continuously monitoring for the quality of the ion formation process in API without the addition of extraneous material (such as labelled compounds or control known compounds) to the system being monitored.