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1. (WO2017034957) METHODS FOR TREATING METASTATIC PANCREATIC CANCER USING COMBINATION THERAPIES COMPRISING LIPOSOMAL IRINOTECAN AND OXALIPLATIN

Pub. No.:    WO/2017/034957    International Application No.:    PCT/US2016/047727
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 20 01:59:59 CEST 2016
IPC: A61K 31/436
A61K 9/127
A61K 31/282
A61K 31/4745
A61K 31/475
A61K 31/513
A61K 31/519
A61P 35/04
Applicants: IPSEN BIOPHARM LTD.
Inventors: BLANCHETTE, Sarah, F.
FITZGERALD, Jonathan, Basil
GADDY, Daniel, F.
HENDRIKS, Bart, S.
KALRA, Ashish
LEE, Helen
BAYEVER, Eliel
Title: METHODS FOR TREATING METASTATIC PANCREATIC CANCER USING COMBINATION THERAPIES COMPRISING LIPOSOMAL IRINOTECAN AND OXALIPLATIN
Abstract:
Combination therapy regimens including liposomal irinotecan, oxaliplatin and 5-fluorouracil are useful in the treatment of pancreatic cancer, including treatment of patients diagnosed with previously untreated metastatic adenocarcinoma of the pancreas. The combination therapy can include the administration of liposomal irinotecan, oxaliplatin, leucovorin and 5-fluorouracil once every two weeks.