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1. (WO2017034954) MICROWELL PLATE WITH LAMINATED MICRO EMBOSSED FILM BOTTOM

Pub. No.:    WO/2017/034954    International Application No.:    PCT/US2016/047721
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 20 01:59:59 CEST 2016
IPC: C12N 5/00
B29C 59/04
B29C 59/10
B29C 59/14
Applicants: STEMONIX INC.
Inventors: PETCAVICH, Robert John
Title: MICROWELL PLATE WITH LAMINATED MICRO EMBOSSED FILM BOTTOM
Abstract:
The current disclosure describes a method of fabricating a n x n where n = 1 to 100 micro well plate that has a transparent film bottom where the film has embossed on the surface micro structures for the facilitation of cell growth and differentiation in particular cardiomyocyte cells derived from human induced pluripotent stem cells. In one embodiment, the micro well plate has an array of 384 locations molded out of thermoplastic onto which a micro embossed film is laminated to the bottom. The micro embossed features are fabricated such that that when the film is laminated to the plate, e.g., with adhesive or via welding, the embossed microstructures are located within the individual microplate well locations.