Search International and National Patent Collections

1. (WO2017034639) METHODS AND COMPOSITIONS FOR ENRICHING FOR A MINOR TEMPLATE AMPLIFICATION PRODUCT IN A MIXED TEMPLATE AMPLIFICATION REACTION

Pub. No.:    WO/2017/034639    International Application No.:    PCT/US2016/035733
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Jun 04 01:59:59 CEST 2016
IPC: C12P 19/34
C12Q 1/68
Applicants: HAYDEN, Tracy, Ann
Inventors: HAYDEN, Tracy, Ann
Title: METHODS AND COMPOSITIONS FOR ENRICHING FOR A MINOR TEMPLATE AMPLIFICATION PRODUCT IN A MIXED TEMPLATE AMPLIFICATION REACTION
Abstract:
A longstanding challenge in forensics is resolving the genetic profile of a minor contributor in a mixed contributor sample. The instant disclosure provides for differentially labeling the products resulting from the amplification of a template from a major contributor relative to that of a minor contributor. Based on this differential labeling, the genetic profile of the minor contributor can be resolved from that of a major contributor.