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1. (WO2017034304) PREPARATION OF ENZYME COMPOSITE AND METHOD FOR PRODUCING TARGET MATERIAL USING SAME
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Pub. No.: WO/2017/034304 International Application No.: PCT/KR2016/009340
Publication Date: 02.03.2017 International Filing Date: 23.08.2016
IPC:
C12N 9/96 (2006.01) ,C12N 15/70 (2006.01) ,C12P 5/02 (2006.01) ,C12P 7/16 (2006.01) ,C12P 7/18 (2006.01)
[IPC code unknown for C12N 9/96][IPC code unknown for C12N 15/70][IPC code unknown for C12P 5/02][IPC code unknown for C12P 7/16][IPC code unknown for C12P 7/18]
Applicants:
한국생명공학연구원 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY [KR/KR]; 대전시 유성구 과학로 125 125, Gwahak-ro, Yuseong-gu, Daejeon 34141, KR
Inventors:
이승구 LEE, Seung Goo; KR
김하성 KIM, Ha Seong; KR
성원재 SEONG, Won Jae; KR
염수진 YEOM, Soo Jin; KR
이대희 LEE, Dae Hee; KR
정흥채 JUNG, Heung Chae; KR
한귀환 HAN, Gui Hwan; KR
Agent:
특허법인 태평양 BAE, KIM & LEE IP GROUP; 서울시 서초구 강남대로 343, 11층 11th Floor, 343, Gangnam-daero, Seocho-gu, Seoul 06626, KR
Priority Data:
10-2015-011978425.08.2015KR
Title (EN) PREPARATION OF ENZYME COMPOSITE AND METHOD FOR PRODUCING TARGET MATERIAL USING SAME
(FR) PRÉPARATION D'UN COMPOSITE ENZYMATIQUE ET PROCÉDÉ DE PRODUCTION DE MATÉRIAU CIBLE L'UTILISANT
(KO) 효소 복합체의 제조 및 이를 이용한 목적물질의 생산 방법
Abstract:
(EN) The present invention relates to an enzyme composite of synthetic enzymes involved in the synthesis of a target material and a method for producing a target material using the same. An enzyme composite is provided that contains fiber-binding domains and two or more kinds of different enzymes involved in the synthesis of a target material, wherein the two or more kinds of different enzymes involved in the synthesis of the target material are connected with fiber-binding domains, respectively. The enzyme composite narrows the physical interval of the enzymes that act on a series of processes of the conversion from a precursor of the target material into the target material, and thus can induce an intermediate product to immediately participate in a next reaction, thereby improving the rate or yield of the overall production of the target material.
(FR) La présente invention concerne un composite enzymatique d'enzymes synthétiques impliquées dans la synthèse d'un matériau cible et un procédé de fabrication d'un matériau cible l'utilisant. L'invention concerne un composite enzymatique qui contient des domaines de liaison de fibres et deux types ou plus de différentes enzymes impliquées dans la synthèse d'un matériau cible, les deux types ou plus de différentes enzymes impliquées dans la synthèse du matériau cible étant liés aux domaines de liaison de fibres, respectivement. Le composite enzymatique diminue l'intervalle physique des enzymes qui agissent sur une série de processus de la conversion d'un précurseur du matériau cible en matériau cible, et peut ainsi induire un produit intermédiaire qui participera immédiatement à une réaction suivante, permettant ainsi d'améliorer la vitesse ou le rendement de la production globale du matériau cible.
(KO) 본 발명은 목적 물질 생합성에 관여하는 합성 효소의 효소 복합체 및 이를 이용한 목적 물질의 생산 방법에 관한 것으로서, 섬유소결합도메인 및 목적 물질 합성에 관여하는 2 종류 이상의 서로 다른 효소들을 포함하고, 목적 물질의 합성에 관여하는 2 종류 이상의 서로 다른 효소들이 각각 섬유소결합도메인과 연결되는 효소 복합체를 제공하며, 이러한 효소 복합체는 목적 물질의 전구체로부터 목적 물질로 전환되는 일련의 과정에 작용하는 효소들의 물리적인 간격을 좁힘으로써 중간 생성물이 즉각적으로 다음 반응에 참여할 수 있도록 유도할 수 있고, 그로 인해 전체적인 목적 물질의 생성의 속도나 수율을 향상시킬 수 있는 효과가 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)