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1. WO2017034244 - PEPTIDE HAVING EFFECT OF PREVENTING OR TREATING CENTRAL NERVOUS SYSTEM DISEASES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT

Publication Number WO/2017/034244
Publication Date 02.03.2017
International Application No. PCT/KR2016/009201
International Filing Date 19.08.2016
IPC
C07K 14/435 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
A61K 38/17 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61K 49/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
C07K 19/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
CPC
A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61K 49/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
Applicants
  • 한양대학교 산학협력단 IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) [KR]/[KR]
Inventors
  • 최제민 CHOI, Je-Min
  • 임상호 LIM, Sangho
Agents
  • 특허법인 충현 CHUNG HYUN PATENT & LAW FIRM
Priority Data
10-2015-011796621.08.2015KR
10-2016-010564219.08.2016KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) PEPTIDE HAVING EFFECT OF PREVENTING OR TREATING CENTRAL NERVOUS SYSTEM DISEASES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT
(FR) PEPTIDE AYANT POUR EFFET DE PRÉVENIR OU TRAITER DES MALADIES DU SYSTÈME NERVEUX CENTRAL ET COMPOSITION PHARMACEUTIQUE POUR LA PRÉVENTION ET LE TRAITEMENT DE MALADIES DU SYSTÈME NERVEUX CENTRAL, CONTENANT CE DERNIER EN TANT QUE PRINCIPE ACTIF
(KO) 중추신경계 질환에 대한 예방 또는 치료효과를 갖는 펩타이드 및 이를 유효성분으로 하는 중추신경계 질환 예방 및 치료용 약학적 조성물
Abstract
(EN) The present invention has a function of enabling the penetration of the blood-brain barrier and the blood-spinal cord barrier of the central nervous system, which have not been significantly penetrated, with excellent efficiency, thereby enabling a rapid, quick, and more efficient therapeutic effect to be obtained through low dose administration. In addition, the present invention enables local administration unlike conventional therapeutic agents, thereby decreasing side effects, and enables local administration of a therapeutic agent at a high concentration, thereby enabling potentially new treatments and prescriptions.
(FR) La présente invention a pour fonction de permettre la pénétration de la barrière hémato-encéphalique et la barrière sang-moelle épinière du système nerveux central, qui n'ont pas été significativement pénétrées, avec une excellente efficacité, ce qui permet d'obtenir un effet thérapeutique rapide, prompt et plus efficace par une administration à faible dose. En outre, la présente invention permet une administration locale à la différence des agents thérapeutiques classiques, ce qui permet de réduire les effets secondaires, et permet l'administration locale d'un agent thérapeutique à une concentration élevée, ce qui permet potentiellement de nouveaux traitements et de nouvelles prescriptions.
(KO) 본 발명은 유의하게 통과시킬 수 없었던 중추신경계의 뇌-혈관 장벽 및 척수-혈관 장벽을 우수한 효율로 투과할 수 있는 기능을 가져, 낮은 함량을 투여하여 신속하고 빠르며, 보다 효율적인 치료효과를 얻을 수 있다. 또한 본 발명은 종래 치료제들에 비해 국소적 투여를 간행할 수 있으므로 부작용이 감소되고, 치료제의 국소적 고농도 투여가 가능하므로, 잠재적 새로운 치료 및 처방이 가능하다.
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