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1. (WO2017033906) METHOD FOR DETECTING RP2-ARHGAP6 GENE

Pub. No.:    WO/2017/033906    International Application No.:    PCT/JP2016/074442
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Wed Aug 24 01:59:59 CEST 2016
IPC: C12N 15/09
C12Q 1/68
Applicants: ASTELLAS PHARMA INC.
アステラス製薬株式会社
NATIONAL CANCER CENTER
国立研究開発法人国立がん研究センター
Inventors: SASAKI, Hiroki
佐々木 博己
ICHIKAWA, Hitoshi
市川 仁
Title: METHOD FOR DETECTING RP2-ARHGAP6 GENE
Abstract:
The present invention addresses the problem of elucidating a polynucleotide which is a novel causative gene for cancer, and providing, as a result, a method for detecting said polynucleotide or a polypeptide encoded thereby, a primer set therefor, and a detection kit. In the detection method, either a fusion gene comprising a portion of the RP2 gene and a portion of the ARHGAP6 gene, or a fusion protein encoded thereby is detected. The primer set includes: a sense primer designed from the portion encoding RP2; and an antisense primer designed from the portion encoding ARHGAP6.