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1. (WO2017033119) COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER METABOLIC DISEASES

Pub. No.:    WO/2017/033119    International Application No.:    PCT/IB2016/055004
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Tue Aug 23 01:59:59 CEST 2016
IPC: A61K 31/00
Applicants: RAO M, Surya
Inventors: RAO M, Surya
Title: COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER METABOLIC DISEASES
Abstract:
The invention relates to the compositions of formula I and formula II or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprises a salt of bile acid and the methods for treating or preventing liver diseases, fatty liver, NASH, bile acid synthesis disorders due to single enzyme defects, gallstones, peroxisomal disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of NASH, fatty liver, liver cirrhosis and Bile acid synthesis disorders due to single enzyme defects, gallstones and peroxisomal disorders.