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1. WO2017033055 - CYCLIC PEPTIDOMIMETICS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS

Publication Number WO/2017/033055
Publication Date 02.03.2017
International Application No. PCT/IB2016/001247
International Filing Date 29.08.2016
IPC
C07K 5/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
02containing at least one abnormal peptide link
C07K 7/56 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
54with at least one abnormal peptide link in the ring
56the cyclisation not occurring through 2,4-diamino-butanoic acid
C07K 5/11 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
10Tetrapeptides
11the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides ; , e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 37/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
06Immunosuppressants, e.g. drugs for graft rejection
A61P 7/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
Applicants
  • UNIWERSYTET WARSZAWSKI [PL]/[PL]
Inventors
  • MISICKA-KESIK, Aleksandra
  • GRABOWSKA, Karolina
  • PUSZKO, Anna
  • NIESCIORUK, Anna
  • SOSNOWSKI, Piotr
  • FEDORCZYK, Bartlomiej
  • TYMECKA, Dagmara
  • WILENSKA, Beata
  • WITKOWSKA, Ewa
Agents
  • ŻEBROWSKA-KUCHARZYK, Agnieszka
Priority Data
PL41370527.08.2015PL
Publication Language English (EN)
Filing Language Polish (PL)
Designated States
Title
(EN) CYCLIC PEPTIDOMIMETICS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS
(FR) PEPTIDOMIMÉTIQUES CYCLIQUES, COMPOSITIONS LES CONTENANT ET LEUR UTILISATION DANS LE TRAITEMENT DE MALADIES ASSOCIÉES À L'ANGIOGENÈSE
Abstract
(EN)
The present invention relates to novel cyclic peptidomimetics, pharmaceutical compositions containing them and their use in the treatment of diseases associated with angiogenesis especially tumors and chronic inflammation in psoriasis, diabetes, degenerative diseases of the eye (ARMD), nephropathy and neuropathy.
(FR)
La présente invention concerne de nouveaux peptidomimétiques cycliques, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de maladies associées à l'angiogenèse, en particulier les tumeurs et l'inflammation chronique dans le psoriasis, le diabète, les maladies dégénératives de l'oeil (ARMD), la néphropathie et la neuropathie.
Also published as
Latest bibliographic data on file with the International Bureau