The invention concerns a device for attaching soft tissue to bone tissue, e.g. a broken ligament or ligament graft (1), comprising a flexible wire (10) provided with several corpuscles (9, 9', 9") fixed along the length of same, and a screw (8) capable of engaging with said corpuscles of the wire (10) when screwed into a bone tunnel (4) by blocking them between the screw pitch and the bone tissue. The wire is capable of forming a free loop (2) for receiving said soft tissue, e.g. a ligament graft, the two branches of said loop being provided with said corpuscles. The wire can also be provided with a closed loop or a crimped needle. The screw is a cannulated screw for receiving a guide pin (6).