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1. (WO2017032881) TOCOTRIENOL DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHOD OF USE IN 5-LIPOXYGENASE RELATED DISEASES
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Pub. No.: WO/2017/032881 International Application No.: PCT/EP2016/070204
Publication Date: 02.03.2017 International Filing Date: 26.08.2016
IPC:
C07D 311/72 (2006.01) ,A61K 31/355 (2006.01)
[IPC code unknown for C07D 311/72][IPC code unknown for A61K 31/355]
Applicants:
UNIVERSITÉ D'ANGERS [FR/FR]; 40 rue de Rennes 49000 Angers, FR
UNIVERSITÄT INNSBRUCK [AT/AT]; Innrain 52 6020 Innsbruck, AT
FRIEDRICH-SCHILLER-UNIVERSITÄT JENA [DE/DE]; Fürstengraben 1 07743 Jena, DE
Inventors:
RICHOMME, Pascal; FR
HELESBEUX, Jean-Jacques; FR
GUILET, David; FR
SERAPHIN, Denis; FR
STUPPNER, Hermann; AT
WALTENBERGER, Birgit; AT
SCHUSTER, Daniela; AT
TEMML, Veronika Sophie; AT
KOEBERLE, Andreas; DE
WERZ, Oliver; DE
Agent:
ICOSA; 83 avenue Denfert-Rochereau 75014 Paris, FR
Priority Data:
15182827.427.08.2015EP
Title (EN) TOCOTRIENOL DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHOD OF USE IN 5-LIPOXYGENASE RELATED DISEASES
(FR) DÉRIVÉS DE TOCOTRIÉNOL, COMPOSITION PHARMACEUTIQUE ET LEUR MÉTHODE D'UTILISATION DANS LES MALADIES LIÉES À LA 5-LIPOXYGÉNASE
Abstract:
(EN) The present invention relates to compounds of formula (III) or to compounds of formula (IV) wherein R1, R2, R3 and R4 are as defined in the claims, and their use in therapeutic treatments of 5-lipoxygenase related diseases such as chronic airway inflammatory or dermatological disorders.
(FR) La présente invention concerne des composés de formule (III) ou des composés de formule (IV) où R1, R2, R3 et R4 sont tels que définis dans les revendications, et leur utilisation dans les traitements thérapeutiques de maladies liées à la 5-lipoxygénase telles que les troubles inflammatoires chroniques des voies respiratoires ou les troubles dermatologiques chroniques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)