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1. (WO2017032871) METHOD OF DIFFERENTIAL DIAGNOSIS OF DEMENTIA WITH LEWY BODIES AND PARKINSON`S DISEASE

Pub. No.:    WO/2017/032871    International Application No.:    PCT/EP2016/070166
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 27 01:59:59 CEST 2016
IPC: G01N 33/68
Applicants: GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS, UNIVERSITAETSMEDIZIN
Inventors: MOLLENHAUER, Brit
SCHNEIDER, Anja
Title: METHOD OF DIFFERENTIAL DIAGNOSIS OF DEMENTIA WITH LEWY BODIES AND PARKINSON`S DISEASE
Abstract:
The present invention is directed to methods of differential diagnosis of dementia with Lewy bodies and/or Parkinson's disease. Methods according to the present disclosure typically comprise a step of isolating exosomes from a sample of cerebrospinal fluid (CSF), and determining the number of exosomes and/or amount of exosomal α-Synuclein in a defined volume of CSF sample.