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1. (WO2017032865) METHOD FOR EVALUATING INDIVIDUAL RADIOSENSITIVITY AND THE RISK OF ADVERSE EFFECTS

Pub. No.:    WO/2017/032865    International Application No.:    PCT/EP2016/070153
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Sat Aug 27 01:59:59 CEST 2016
IPC: C12Q 1/68
Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
INSERM
UNIVERSITÉ PARIS-SUD
UNIVERSITÉ PARIS-DIDEROT
INSTITUT REGIONAL DU CANCER DE MONTPELLIER
UNIVERSITE DE MONTPELLIER
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAÏ
UNIVERSITY OF ROCHESTER
Inventors: SCHMITZ, Annette
BAIJER, Jan
AZRIA, David
KERNS, Sarah
PERDRY, Hervé
Title: METHOD FOR EVALUATING INDIVIDUAL RADIOSENSITIVITY AND THE RISK OF ADVERSE EFFECTS
Abstract:
The present invention relates to a single nucleotide polymorphism (SNP) rs3815496 or any SNP having 100 % of linkage disequilibrium with this SNP as a biomarker for assessing the risk of developing adverse effects after radiotherapy in a subject, in particular acute and/or subacute dermatitis and lymphocyte apoptosis.