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1. (WO2017032855) COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF

Pub. No.:    WO/2017/032855    International Application No.:    PCT/EP2016/070132
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Fri Aug 26 01:59:59 CEST 2016
IPC: C07K 14/51
A61K 38/12
A61K 38/18
C07K 7/64
Applicants: HISTIDE AG
Inventors: ZOUANI, Omar F.
Title: COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF
Abstract:
The present disclosure provides a cyclic peptide, or a variant or analog thereof, or a cyclic peptidomimetic, with between 15 and 35 amino acids, having a growth factor receptor-binding capability and comprising a peptide with four amino acids PEP1, and a peptide with five amino acids PEP2; wherein PEP1 is selected from the group consisting of SAIS, SSLS, NAIS, SATS, SPIS, EPIS, SPIN, KPLS, EPLP, EPLT, SNIT, RSVK and RPVQ; and wherein PEP2 is selected from the group consisting of LKNYQ, LKVYP, LKKYR, LRKHR, LKYHY, KFKYE, YGKIP, YKQYE, DHHKD, EQLSN, IGEMS, LGEMS, KEVQV and KKATV.