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1. (WO2017032798) NOVEL INSULIN DERIVATIVES AND THE MEDICAL USES HEREOF
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Pub. No.: WO/2017/032798 International Application No.: PCT/EP2016/069972
Publication Date: 02.03.2017 International Filing Date: 24.08.2016
IPC:
C07K 14/62 (2006.01) ,A61K 38/28 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
62
Insulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
28
Insulins
Applicants:
NOVO NORDISK A/S [DK/DK]; Novo Allé 2880 Bagsværd, DK
Inventors:
MADSEN, Peter; DK
MURRAY, Anthony; DK
MÜNZEL, Martin; DK
HJØRRINGGAARD, Claudia Ulrich; DK
HOSTRUP, Susanne; DK
GLENDORF, Tine; DK
NORRMAN, Mathias; DK
FLEDELIUS, Christian; DK
Priority Data:
15182282.225.08.2015EP
Title (EN) NOVEL INSULIN DERIVATIVES AND THE MEDICAL USES HEREOF
(FR) NOUVEAUX DÉRIVÉS D'INSULINE ET LEURS UTILISATIONS MÉDICALES
Abstract:
(EN) The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.
(FR) L'invention se rapporte aux domaines thérapeutiques des médicaments destinés à traiter des états pathologiques associés au diabète. Plus spécifiquement, l'invention concerne de nouveaux dérivés acylés d'analogues d'insuline humaine. Des compositions pharmaceutiques comprenant lesdits dérivés d'insuline, et l'utilisation de ces dérivés dans le traitement ou la prévention d'états pathologiques associés au diabète sont en outre décrites.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)