A power supply apparatus with a data transmission function comprises a housing (10) and a circuit board (20). At least a voltage conversion module (24) and a USB transmission and power supply module (23) are disposed on the circuit board. A power supply interface (30) providing multiple supply voltages is provided on the housing, the power supply interface being electrically connected to the voltage conversion module. Multiple USB interfaces (40) are further provided on the housing, the USB interfaces being electrically connected to the USB transmission and power supply module. The power supply apparatus not only can meet charging demands of various electronic products, but also can implement data transmission.