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1. (WO2017032303) POLYPEPTIDE CARRIER FOR PRESENTING TARGET POLYPEPTIDE AND USES THEREOF
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Pub. No.: WO/2017/032303 International Application No.: PCT/CN2016/096481
Publication Date: 02.03.2017 International Filing Date: 24.08.2016
IPC:
C12N 15/51 (2006.01) ,C12N 15/62 (2006.01) ,C07K 19/00 (2006.01) ,C12N 7/04 (2006.01) ,A61K 39/385 (2006.01) ,A61K 39/29 (2006.01) ,A61P 31/20 (2006.01)
[IPC code unknown for C12N 15/51][IPC code unknown for C12N 15/62][IPC code unknown for C07K 19][IPC code unknown for C12N 7/04][IPC code unknown for A61K 39/385][IPC code unknown for A61K 39/29][IPC code unknown for A61P 31/20]
Applicants:
厦门大学 XIAMEN UNIVERSITY [CN/CN]; 中国福建省厦门市 思明区思明南路422号 No.422 Si Ming Nan Road, Siming District Xiamen, Fujian 361005, CN
厦门万泰沧海生物技术有限公司 XIAMEN INNOVAX BIOTECH CO., LTD. [CN/CN]; 中国福建省厦门市 海沧区新园路130号 No.130, Xinyuan Road, Haicang Xiamen, Fujian 361022, CN
Inventors:
张天英 ZHANG, Tianying; CN
袁权 YUAN, Quan; CN
郭雪染 GUO, Xueran; CN
张莹 ZHANG, Ying; CN
赵勤俭 ZHAO, Qinjian; CN
张军 ZHANG, Jun; CN
夏宁邵 XIA, Ningshao; CN
Agent:
中国国际贸易促进委员会专利商标事务所 CCPIT PATENT AND TRADEMARK LAW OFFICE; 中国北京市 西城区阜成门外大街2号万通新世界广场8层 8th Floor, Vantone New World Plaza, 2 Fuchengmenwai Street, Xicheng District Beijing 100037, CN
Priority Data:
201510523187.825.08.2015CN
Title (EN) POLYPEPTIDE CARRIER FOR PRESENTING TARGET POLYPEPTIDE AND USES THEREOF
(FR) POLYPEPTIDE SUPPORT POUR LA PRÉSENTATION D'UN POLYPEPTIDE CIBLE ET UTILISATIONS ASSOCIÉES
(ZH) 一种用于展示目的多肽的多肽载体及其用途
Abstract:
(EN) Provided is a nucleic acid molecular, comprising a nucleotide sequence coding a polypeptide carrier. Also provided are a recombinant protein comprising the polypeptide carrier and a target polypeptide, and uses of the nucleic acid molecular and the recombinant protein. Also provided is a vaccine or pharmaceutical composition that can be used for prevention, alleviation, or treatment of HBV infections or HBV infection-related diseases (for example, hepatitis B), the composition comprising the polypeptide carrier and a recombinant protein from an HBV epitope.
(FR) La présente invention concerne une molécule d'acide nucléique comprenant une séquence nucléotidique codant un polypeptide support. L'invention concerne également une protéine recombinée comprenant le polypeptide support et un polypeptide cible, et des utilisations de la molécule d'acide nucléique et de la protéine recombinée. L'invention concerne également un vaccin ou une composition pharmaceutique qui peut être utilisé(e) pour prévenir, atténuer ou traiter les infections au VHB ou les maladies associées à l'infection au VHB (par exemple l'hépatite B), la composition comprenant le polypeptide support et une protéine recombinée à partir d'un épitope du VHB.
(ZH) 提供一种核酸分子,其包含编码多肽载体的核苷酸序列。还提供包含该多肽载体和目的多肽的重组蛋白以及该核酸分子和该重组蛋白的用途。还提供可用于预防、减轻或治疗HBV感染或与HBV感染相关的疾病(例如乙肝)的疫苗或药物组合物,其包含该多肽载体和来自HBV表位的重组蛋白。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)