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1. (WO2017031993) CORRELATION BETWEEN LONG NON-CODING RNA H19 AND CANCER PLATINUM-BASED CHEMOTHERAPEUTIC DRUG RESISTANCE

Pub. No.:    WO/2017/031993    International Application No.:    PCT/CN2016/079538
Publication Date: Fri Mar 03 00:59:59 CET 2017 International Filing Date: Tue Apr 19 01:59:59 CEST 2016
IPC: A61K 48/00
A61K 31/7088
A61P 35/00
C12Q 1/68
C12N 15/113
Applicants: ZHEJIANG UNIVERSITY
浙江大学
Inventors: HUA, Yuejin
华跃进
ZHENG, Zhiguo
郑智国
XU, Hong
徐虹
Title: CORRELATION BETWEEN LONG NON-CODING RNA H19 AND CANCER PLATINUM-BASED CHEMOTHERAPEUTIC DRUG RESISTANCE
Abstract:
Provided are uses of an agent capable of reducing and/or inhibiting the expression of long non-coding RNA H19 in cancer cells in the preparation of a medicine for treating or preventing cancers, and in the preparation of a medicine for reducing the resistance of cancers to the platinum-based chemotherapeutic drug. Also provided is a use of an agent capable of detecting the expression of a long non-coding RNA H19 in the preparation of a test kit, the test kit being used for diagnosing the occurrence of cancers or predicting a cancer relapse, and for predicting, detecting or diagnosing the resistance to the platinum-based chemotherapeutic drug of a cancer patient.