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1. WO2017029407 - ALBUMIN VARIANTS AND CONJUGATES

Publication Number WO/2017/029407
Publication Date 23.02.2017
International Application No. PCT/EP2016/069748
International Filing Date 19.08.2016
IPC
C07K 14/765 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
76Albumins
765Serum albumin, e.g. HSA
CPC
A61K 38/385
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
38Albumins
385Serum albumin
A61K 47/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
A61K 47/643
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
C07K 14/765
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
76Albumins
765Serum albumin, e.g. HSA
C07K 2319/31
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
31fusions, other than Fc, for prolonged plasma life, e.g. albumin
Applicants
  • ALBUMEDIX A/S [DK]/[DK]
Inventors
  • DELAHAY, Karen, Ann
  • FINNIS, Christopher, John, Arthur
  • NICHOLLS, Karl, Michael
Agents
  • WILLIAMS, Rachel
Priority Data
15181822.620.08.2015EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ALBUMIN VARIANTS AND CONJUGATES
(FR) VARIANTS DE L'ALBUMINE ET LEURS CONJUGUÉS
Abstract
(EN)
The present invention relates to conjugation-competent albumins and albumin-related polypeptides, and their conjugates with at least one moiety, and to polynucleotides encoding them.
(FR)
La présente invention concerne des albumines aptes à la conjugaison et des polypeptides liés à l'albumine, ainsi que leurs conjugués avec au moins une fraction, et des polynucléotides codant pour celles-ci.
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