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1. WO2017024182 - GENETICALLY ENCODED INTRINSICALLY DISORDERED STEALTH POLYMERS FOR DELIVERY AND METHODS OF USING SAME

Publication Number WO/2017/024182
Publication Date 09.02.2017
International Application No. PCT/US2016/045655
International Filing Date 04.08.2016
IPC
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
CPC
A61K 2039/6031
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
60characteristics by the carrier linked to the antigen
6031Proteins
A61K 31/337
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Applicants
  • DUKE UNIVERSITY [US]/[US]
Inventors
  • CHILKOTI, Ashutosh
  • BANSKOTA, Samagya
  • YOUSEFPOUR, Parisa
  • BHATTACHARYYA, Jayanta
Agents
  • COX, Julia, M.
Priority Data
62/200,72604.08.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENETICALLY ENCODED INTRINSICALLY DISORDERED STEALTH POLYMERS FOR DELIVERY AND METHODS OF USING SAME
(FR) POLYMÈRES DISCRETS INTRINSÈQUEMENT DÉSORDONNÉS CODÉS GÉNÉTIQUEMENT POUR ADMINISTRATION ET LEURS PROCÉDÉS D'UTILISATION
Abstract
(EN)
Provided herein are conjugates including a polypeptide and one or more drug molecules. The polypeptide includes one or more charged motifs, and may further include one or more uncharged motifs. The conjugates may be used to effectively deliver the drug molecule to a subject.
(FR)
L'invention concerne des conjugués comprenant un polypeptide et une ou plusieurs molécules de médicament. Le polypeptide comprend un ou plusieurs motifs chargés et peut, en outre, comprendre un ou plusieurs motifs non chargés. Les conjugués peuvent être utilisés pour administrer de façon efficace la molécule de médicament à un sujet.
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