Processing

Please wait...

Settings

Settings

Goto Application

1. WO2017022728 - CNP CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE

Publication Number WO/2017/022728
Publication Date 09.02.2017
International Application No. PCT/JP2016/072562
International Filing Date 01.08.2016
Chapter 2 Demand Filed 31.05.2017
IPC
C07K 7/54 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
54with at least one abnormal peptide link in the ring
A61K 8/64 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
A61K 9/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
06Ointments; Bases therefor
A61K 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
A61K 9/107 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions
A61K 9/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
12Aerosols; Foams
CPC
A61K 2800/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
10General cosmetic use
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
A61K 8/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
Applicants
  • 株式会社イギス IGISU CO., LTD. [JP]/[JP]
Inventors
  • 遠藤京子 ENDO, Kyoko
  • 遠藤陽央莉 ENDO, Yori
Agents
  • 葛和清司 KUZUWA, Kiyoshi
Priority Data
2015-15272231.07.2015JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) CNP CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE
(FR) PEPTIDE CYCLIQUE CNP ET MÉDICAMENT, PRÉPARATION À USAGE EXTERNE ET PRODUIT COSMÉTIQUE, CONTENANT TOUS LEDIT PEPTIDE CYCLIQUE
(JA) CNP環状ペプチド並びに該環状ペプチドを含む医薬品、外用剤および化粧料
Abstract
(EN)
The present invention addresses the problem of providing: a novel peptide which can exert the medicinal effect or efficacy thereof rapidly and has a long duration of remission; and a medicine and an external preparation, particularly a prophylactic or therapeutic agent for dermatitis, rough skin, rhinitis, alopecia or thinning hair, a hair growth agent, an anti-depilation agent, an antipruritic agent, a skin care product and the like, each of which contains the peptide. According to the present invention, the problem can be solved by providing a cyclic peptide comprising the amino acid sequence represented by formula I wherein the amino acid sequence does not contain a peptide bond other than peptide bonds formed between amino acid residues that constitute the amino acid sequence, or a derivative of the cyclic peptide, or a pharmaceutically acceptable salt of the cyclic peptide or the derivative.
(FR)
Le problème de la présente invention concerne : un nouveau peptide qui peut exercer un effet médicinal ou l'efficacité correspondante rapidement et qui présente une longue durée de rémission; et un médicament et une préparation à usage externe, en particulier un agent prophylactique ou thérapeutique pour la dermatite, la peau rugueuse, la rhinite, l'alopécie ou les cheveux clairsemés, un agent de croissance des cheveux, un agent anti-épilation, un agent antiprurigineux, un produit de soin de la peau et similaires, dont chacun contient le peptide. Selon la présente invention, la solution du problème porte sur un peptide cyclique comprenant la séquence d'acides aminés représentée par la formule I, dans laquelle la séquence d'acides aminés ne contient pas de liaison peptidique autre que des liaisons peptidiques formées entre des résidus d'acides aminés qui constituent la séquence d'acides aminés, ou un dérivé du peptide cyclique ou un sel pharmaceutiquement acceptable de ce peptide cyclique ou du dérivé.
(JA)
本発明は、薬効、効能の効果発現が早く寛解維持期間が長い新規ペプチド、これを含む医薬や外用剤、特に皮膚炎、肌荒れ、鼻炎、脱毛症、薄毛に対する予防または治療剤や発毛剤、育毛剤、鎮痒剤、スキンケア用品などを提供することを目的とする。本発明は、式Iで表されるアミノ酸配列を有し、当該アミノ酸配列が、当該アミノ酸配列を構成するアミノ酸同士以外のペプチド結合を有さない、環状ペプチドもしくはその誘導体またはこれらの薬学的に許容可能な塩を提供することにより、上記目的が達された。
Latest bibliographic data on file with the International Bureau