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1. (WO2017020034) USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT SKELETAL DYSPLASIA
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/020034 International Application No.: PCT/US2016/044968
Publication Date: 02.02.2017 International Filing Date: 01.08.2016
IPC:
A61K 38/22 (2006.01) ,A61K 38/17 (2006.01) ,A61P 19/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
08
for bone diseases, e.g. rachitism, Paget's disease
Applicants: BIOMARIN PHARMACEUTICAL INC.[US/US]; 105 Digital Drive Novato, CA 94949, US
Inventors: BULLENS, Sherry; US
BUNTING, Stuart; US
CHOU, Tianwei; US
OKHAMAFE, Augustus, O.; US
PRICE, Christopher, P.; DE
WENDT, Daniel, J.; US
YAP, Clarence; US
Agent: NEVILLE, Katherine, L.; US
Priority Data:
62/199,08130.07.2015US
62/320,70411.04.2016US
Title (EN) USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT SKELETAL DYSPLASIA
(FR) UTILISATION DE VARIANTS DU PEPTIDE NATRIURÉTIQUE DE TYPE C POUR TRAITER LES DYSPLASIES DU SQUELETTE
Abstract:
(EN) The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
(FR) La présente divulgation concerne l'utilisation de variants du peptide natriurétique de type C (CNP), et de nouvelles compositions pharmaceutiques et formulations les contenant dans le traitement des dysplasies du squelette, d'un ou de plusieurs symptômes des dysplasies du squelette, tels que la croissance ou la vitesse de croissance des os longs, et autres troubles accompagnés d'une dysplasie du squelette et/ou d'un symptôme ou d'une composante associé(e) au CNP.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)