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1. (WO2017019925) FUCOSIDASE INHIBITORS

Pub. No.:    WO/2017/019925    International Application No.:    PCT/US2016/044607
Publication Date: Fri Feb 03 00:59:59 CET 2017 International Filing Date: Sat Jul 30 01:59:59 CEST 2016
IPC: C07D 211/46
C07D 211/74
A61K 31/445
A61P 35/00
Applicants: HORIZON ORPHAN LLC
Inventors: ZANKEL, Todd, C.
ISBELL, Sara, Louise
KO, Amanda, Anne
Title: FUCOSIDASE INHIBITORS
Abstract:
The present disclosure relates, in general, to compounds useful as inhibitors of fucosidase enzymes, and to methods and compositions for the treatment of tumors or cancers, such as liver disorders and liver tumors (e.g., hepatocellular carcinoma), with a compound as disclosed herein.