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1. WO2017019783 - SYSTEMS, APPARATUS, AND METHODS RELATED TO MODELING, MONITORING, AND/OR MANAGING METABOLISM

Publication Number WO/2017/019783
Publication Date 02.02.2017
International Application No. PCT/US2016/044288
International Filing Date 27.07.2016
IPC
A61B 5/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
08Measuring devices for evaluating the respiratory organs
CPC
A61B 2560/0223
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
02Operational features
0223of calibration, e.g. protocols for calibrating sensors
A61B 2560/0247
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
02Operational features
0242adapted to measure environmental factors, e.g. temperature, pollution
0247for compensation or correction of the measured physiological value
A61B 5/0816
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
0816Measuring devices for examining respiratory frequency
A61B 5/082
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
082Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
A61B 5/083
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
A61B 5/0833
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
0833Measuring rate of oxygen consumption
Applicants
  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US]/[US]
  • SIEGEL, Andrew M. [US]/[US]
  • FERRAIOLO, Christopher [US]/[US]
  • ZOGBI, George [US]/[US]
Inventors
  • SIEGEL, Andrew M.
  • FERRAIOLO, Christopher
  • ZOGBI, George
  • CANDELL, Lawrence M.
  • SHAW, Gary A.
Agents
  • TEJA, Joseph, Jr.
  • BLINKA, Thomas A.
  • LIBKA, Hilary J.
Priority Data
62/197,32427.07.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEMS, APPARATUS, AND METHODS RELATED TO MODELING, MONITORING, AND/OR MANAGING METABOLISM
(FR) SYSTÈMES, APPAREIL ET PROCÉDÉS SE RAPPORTANT À LA MODÉLISATION, LA SURVEILLANCE ET/OU LA GESTION DU MÉTABOLISME
Abstract
(EN)
Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism of a subject include measuring a respiratory quotient (RQ) level in a subject and/or optimizing and executing a nonlinear feedback model to model energy substrate utilization in the subject based on at least one of a macronutrient composition and caloric value of food consumed by the subject, an intensity and duration of activity by the subject, a rate and maximum capacity of glycogen storage in the subject, a rate and maximum capacity of de novo lipogenesis in the subject, a quality and duration of sleep by the subject, and/or an RQ level in the subject.
(FR)
La présente invention concerne des systèmes, un appareil et des procédés se rapportant à la modélisation, la surveillance et/ou la gestion du métabolisme d'un sujet. Le procédé consiste à mesurer un niveau de quotient respiratoire (RQ) chez un sujet et/ou optimiser et exécuter un modèle non-linéaire de réaction afin de modéliser le recours à un substrat énergétique chez le sujet sur la base d'au moins l'un ou l'autre d'une composition de macro-nutriments et d'une valeur calorique d'aliments consommés par le sujet, d'une intensité et d'une durée d'activité par le sujet, d'un taux et d'une capacité maximale de stockage de glycogène chez le sujet, d'un taux et d'une capacité maximale de la lipogenèse de novo chez le sujet, d'une qualité et d'une durée du sommeil chez le sujet et/ou d'un niveau de RQ chez le sujet.
Also published as
Latest bibliographic data on file with the International Bureau