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1. (WO2017019602) REDUCED SAMPLE VOLUME FOR SENSING OF ANALYTES GENERATED BY REVERSE IONTOPHORESIS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/019602 International Application No.: PCT/US2016/043862
Publication Date: 02.02.2017 International Filing Date: 25.07.2016
IPC:
A61B 5/00 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/1477 (2006.01) ,A61B 5/1486 (2006.01) ,A61N 1/30 (2006.01) ,G01N 27/26 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468
using chemical or electrochemical methods, e.g. by polarographic means
1477
non-invasive
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1486
using enzyme electrodes, e.g. with immobilised oxidase
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1
Electrotherapy; Circuits therefor
18
Applying electric currents by contact electrodes
20
continuous direct currents
30
Apparatus for iontophoresis or cataphoresis
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
Applicants: UNIVERSITY OF CINCINNATI[US/US]; 2624 Clifton Avenue Cincinnati, OH 45221-0623, US
ECCRINE SYSTEMS, INC.[US/US]; 9078 Union Centre Boulevard West Chester Township, OH 45069, US
Inventors: HEIKENFELD, Jason, C.; US
JAJACK, Andrew; US
SHEETZ, Elizabeth; US
Agent: CONKLIN, Elizabeth, A.; US
BELLAMY, Glenn; US
ARDIZZONE, Timothy, D.; US
AHRENS, Gregory, F.; US
BENINTENDI, Steven, W; US
Priority Data:
62/196,54124.07.2015US
62/328,90728.04.2016US
62/357,64301.07.2016US
Title (EN) REDUCED SAMPLE VOLUME FOR SENSING OF ANALYTES GENERATED BY REVERSE IONTOPHORESIS
(FR) VOLUME D'ÉCHANTILLON RÉDUIT POUR LA DÉTECTION D'ANALYTES GÉNÉRÉS PAR IONTOPHORÈSE INVERSE
Abstract:
(EN) A device (100) for sensing biofluid placed on skin (12) with at least one pre-existing pathway (14) includes a first analyte-specific sensor (120) for sensing a first analyte in the biofluid and a volume-reduced pathway between skin (12) and the first analyte-specific sensor (120) configured to allow an advective flow of the biofluid from the at least one pre-existing pathway (14) toward the first analyte-specific sensor (120). The first analyte-specific sensor (120) does not consume the first analyte. The device (100) further includes an iontophoresis electrode (150) and a counter electrode (152) for bringing the first analyte into the at least one pre-existing pathway. The biofluid may be more than 50% interstitial fluid or more than 50% sweat. The device (100) may also include at least one of a wicking collector (136), a wicking coupler (130), or a wicking pump (138).
(FR) La présente invention concerne un dispositif (100) de détection de fluide biologique placé sur la peau (12) avec au moins une voie préexistante (14) qui comprend un premier capteur d'analyte spécifique (120) pour détecter un premier analyte dans le fluide biologique et une voie à volume réduit entre la peau (12) et le premier capteur d'analyte-spécifique (120) configuré pour permettre à un écoulement de transport du fluide biologique depuis l'au moins une voie préexistante (14) vers le premier capteur d'analyte spécifique (120). Le premier capteur d'analyte spécifique (120) ne consomme pas le premier analyte. Le dispositif (100) comprend en outre une électrode d'iontophorèse (150) et une contre-électrode (152) pour amener le premier analyte dans l'au moins une voie préexistante. Le fluide biologique peut comprendre plus de 50 % de liquide interstitiel ou plus de 50 % de transpiration. Le dispositif (100) peut comprendre en outre au moins l'un d'un collecteur à effet de mèche (136), un coupleur à effet de mèche (130), ou une pompe à effet de mèche (138).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)