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1. (WO2017019593) METHODS OF REDUCING THE NEED FOR SURGERY IN PATIENTS SUFFERING FROM BENIGN PROSTATIC HYPERPLASIA
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Pub. No.: WO/2017/019593 International Application No.: PCT/US2016/043850
Publication Date: 02.02.2017 International Filing Date: 25.07.2016
IPC:
A61K 38/10 (2006.01) ,A61P 13/08 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
08
of the prostate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
NYMOX CORPORATION [US/US]; 777 Terrace Avenue Hasbrouck Heights, New Jersey 07604, US
Inventors:
AVERBACK, Paul; BS
Agent:
DOODY, Patrick A.; US
PEREZ, Robert C.; US
BARUFKA, Jack S.; US
BELL, Emily T.; US
SWEIGART, Raymond L.; US
ATKINS, William P.; US
BANSAL, Manu; US
BEDGOOD, Robert M.; US
BLAISE, Bradford C.; US
BLAYLOCK, Richard L.; US
COLLINS, Bryan P.; US
DANIELSON, Mark J.; US
DATTA, Madhumita; US
DAVE, Raj S.; US
DAVOUDIAN-MOGHADDAM, Keyvan; US
DEMARCO, A. John; US
DORSEY, Christopher K.; US
ESPLIN, D. Benjamin; US
FINKEL, Evan; US
FUHRER, Robert M.; US
GATTO, James G.; US
GU, Qian; US
HERNANDEZ, Eric Rico; US
HOFFMAN, Jean-Paul G.; US
JADDU, Maithreyi; US
JAFFER, David H.; US
JAKOPIN, David A.; US
KENDRICK, Mark R.; US
KIERSZ, Benjamin L.; US
KOO, Hean L.; US
LAIR, Christophe F.; US
MACAULAY, John M.; US
MEHOK, Michelle L.; US
LATTA, Robert; US
ROBINSON, Carmen K.; US
SCADE, Jaclyn A.; US
SCHICK, Ian C.; US
SHERIFF, Jeffrey T.; US
SIRILLA, George A.; US
STEINBUSCH, Otto L.; US
TOTO, Carolyn S.; US
WANG, Tairan; US
WETHERELL, John R. Jr.; US
WISE, Roger R.; US
ZAITLEN, Richard H.; US
ZHANG, Ngai; US
ZOU, Zhiwei; US
Priority Data:
14/808,73124.07.2015US
Title (EN) METHODS OF REDUCING THE NEED FOR SURGERY IN PATIENTS SUFFERING FROM BENIGN PROSTATIC HYPERPLASIA
(FR) MÉTHODES DE RÉDUCTION DE LA NÉCESSITÉ D'UNE CHIRURGIE CHEZ DES PATIENTS ATTEINTS D'HYPERPLASIE BÉNIGNE DE LA PROSTATE
Abstract:
(EN) The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors using compounds based on small peptides in combination with additional active agent(s). The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier to a mammal in need thereof. Carrying out the method unexpectedly reduces the need for subsequent invasive surgical intervention.
(FR) Les modes de réalisation de l'invention comprennent des méthodes de traitement d'affections nécessitant le retrait ou la destruction d'éléments cellulaires, tels que des tumeurs bénignes ou malignes, à l'aide de composés à base de petits peptides combinés à un ou des agent(s)actif(s) supplémentaire(s). Ladite méthode comprend, mais sans y être limitée, une étape d'administration desdits composés par voie intramusculaire, orale, intraveineuse, intrathécale, intratumorale, intranasale, topique, transdermique, etc., soit seuls, soit conjugués à un excipient, à un mammifère nécessitant un tel traitement. La mise en oeuvre du procédé réduit étonnamment la nécessité d'une intervention chirurgicale invasive subséquente.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)