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1. WO2017018815 - PROCESS FOR PURIFYING AN AMPHIPHILIC BLOCK COPOLYMER, AMPHIPHILIC BLOCK COPOLYMER OBTAINED THEREFROM, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Publication Number WO/2017/018815
Publication Date 02.02.2017
International Application No. PCT/KR2016/008264
International Filing Date 28.07.2016
IPC
C08F 6/28 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
6Post-polymerisation treatments
26Treatment of polymers prepared in bulk
28Purification
C08F 299/00 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
299Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers
A61K 9/127 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61K 31/337 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
A61K 47/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
CPC
A61K 31/337
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
A61K 47/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 9/107
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions ; ; Emulsion preconcentrates; Micelles
A61K 9/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
19lyophilised ; , i.e. freeze-dried, solutions or dispersions
C08G 63/664
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
63Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
66Polyesters containing oxygen in the form of ether groups
664derived from hydroxy carboxylic acids
C08G 63/90
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
63Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
88Post-polymerisation treatment
90Purification; Drying
Applicants
  • SAMYANG BIOPHARMACEUTICALS CORPORATION [KR]/[KR]
Inventors
  • KIM, Bong Oh
  • KIM, Ji Yeong
  • KIM, Hye Rim
  • MIN, Bum Chan
  • SEO, Min Hyo
  • LEE, Sa Won
  • YI, Yil Woong
  • CHO, Joong Woong
  • CHOI, In Ja
Agents
  • HANSUNG INTELLECTUAL PROPERTY
Priority Data
10-2015-010662528.07.2015KR
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR PURIFYING AN AMPHIPHILIC BLOCK COPOLYMER, AMPHIPHILIC BLOCK COPOLYMER OBTAINED THEREFROM, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
(FR) PROCÉDÉ DE PURIFICATION D'UN COPOLYMÈRE À BLOCS AMPHIPHILE, COPOLYMÈRE À BLOCS AMPHIPHILE OBTENU SELON LEDIT PROCÉDÉ, ET COMPOSITION PHARMACEUTIQUE CONTENANT LEDIT COPOLYMÈRE
Abstract
(EN)
A method for purifying an amphiphilic block copolymer by sublimation with suppressing the molecular weight reduction, an amphiphilic block copolymer composition obtained by the purification method, and a pharmaceutical composition comprising the amphiphilic block copolymer composition are provided.
(FR)
L’invention concerne un procédé de purification d'un copolymère à blocs amphiphile par sublimation avec maîtrise de la diminution de sa masse moléculaire, une composition de copolymère à blocs amphiphile obtenue par ce procédé de purification, et une composition pharmaceutique comprenant ladite composition de copolymère à blocs amphiphile.
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