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1. (WO2017018404) COMPOSITION CONTAINING CYCLIC DIPEPTIDE AND SWEETENING AGENT
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Pub. No.: WO/2017/018404 International Application No.: PCT/JP2016/071817
Publication Date: 02.02.2017 International Filing Date: 26.07.2016
IPC:
A61K 38/00 (2006.01) ,A61K 31/216 (2006.01) ,A61K 31/7004 (2006.01) ,A61K 31/704 (2006.01) ,A61P 3/04 (2006.01) ,A61P 3/10 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
216
of acids having aromatic rings, e.g. benactizyne, clofibrate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7004
Monosaccharides having only carbon, hydrogen and oxygen atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
04
Anorexiants; Antiobesity agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants: SUNTORY HOLDINGS LIMITED[JP/JP]; 1-40, Dojimahama 2-chome, Kita-ku, Osaka-shi, Osaka 5308203, JP
Inventors: SUZUKI, Toshihide; JP
HIRAKI, Natsumi; JP
Agent: ONO, Shinjiro; JP
KOBAYASHI, Yasushi; JP
TAKEUCHI, Shigeo; JP
YAMAMOTO, Osamu; JP
Priority Data:
2015-14765227.07.2015JP
Title (EN) COMPOSITION CONTAINING CYCLIC DIPEPTIDE AND SWEETENING AGENT
(FR) COMPOSITION CONTENANT UN DIPEPTIDE CYCLIQUE ET UN ÉDULCORANT
(JA) 環状ジペプチド及び甘味料を含有する組成物
Abstract:
(EN) Provided is a composition which has excellent biological safety and enables the enhancement of a GLP-1 secretion promotion effect associated with a sweetening agent. The ratio of the content of a cyclic dipeptide or a salt thereof to the content of a sweetening agent in the composition is adjusted to a value falling within a specified range. In this manner, the GLP-1 secretion promotion effect associated with the sweetening agent can be enhanced.
(FR) La présente invention concerne une composition qui présente une excellente sécurité biologique et permet l'amélioration d'un effet de promotion de sécrétion de GLP-1 associé à un édulcorant. Le rapport entre la teneur d'un dipeptide cyclique ou d'un de ses sels et la teneur d'un édulcorant dans la composition est ajusté à une valeur se trouvant à l'intérieur d'une plage spécifiée. De cette manière, l'effet de promotion de sécrétion de GLP-1 associé à l'édulcorant peut être amélioré.
(JA) 生体安全性に優れ、かつ、甘味料に起因するGLP-1分泌促進効果を増強することができる組成物を提供する。 組成物中の環状ジペプチド又はその塩の含有量と甘味料の含有量の比率を特定の範囲内にする。これにより、甘味料によるGLP-1分泌促進効果が増強される。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)