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1. (WO2017017669) PRO-DRUGS AND RELATED METHODS

Pub. No.:    WO/2017/017669    International Application No.:    PCT/IL2016/050749
Publication Date: Fri Feb 03 00:59:59 CET 2017 International Filing Date: Thu Jul 14 01:59:59 CEST 2016
IPC: C07D 339/08
Applicants: APOSENSE LTD.
Inventors: ZIV, Ilan
Title: PRO-DRUGS AND RELATED METHODS
Abstract:
The invention relates to Pro-drugs, comprising red-ox-sensitive cleavage sites. The compounds may be utilized in medical practice for targeting of si RNA, antisense oligonucleotides or protein-based therapeutics to the cytoplasmatic compartment of cells both in vitro or in vivo, in a subject in need.