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1. WO2017017469 - CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS

Publication Number WO/2017/017469
Publication Date 02.02.2017
International Application No. PCT/GB2016/052332
International Filing Date 28.07.2016
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
5
Compounds containing elements of the 3rd Group of the Periodic System
02
Boron compounds
C07F 5/02 (2006.01)
CPC
C07F 5/02
Applicants
  • THE UNIVERSITY OF MANCHESTER [GB/GB]; Oxford Road Manchester M13 9PL, GB
Inventors
  • BROUGH, David; GB
  • ALLAN, Stuart McRae; GB
  • FREEMAN, Sally; GB
  • BALDWIN, Alex George; GB
Agents
  • WELLS, Andrew; GB
  • HGF LIMITED; 4th Floor, Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG, GB
Priority Data
1513481.030.07.2015GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS
(FR) DÉRIVÉS DE DIARYLBORON CYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS D'INFLAMMASOME NLRP3
Abstract
(EN)
Inhibitor compounds are disclosed. The compounds are effective in the treatment of diseases or conditions in which interleukin 1 β activity is implicated. Methods of synthesis of the compounds, as well as pharmaceutical compositions comprising the compounds are also disclosed.
(FR)
L'invention concerne des composés inhibiteurs. Les composés sont efficaces dans le traitement de maladies ou d'états dans lesquels l'activité de l'interleukine 1β est impliquée. L'invention concerne également des méthodes de synthèse des composés, ainsi que des compositions pharmaceutiques comprenant les composés.
Also published as
Latest bibliographic data on file with the International Bureau