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1. (WO2017017294) DIRUTHENIUM COMPOUNDS WITH OPEN-PADDLEWHEEL STRUCTURE AND THE INTERACTION THEREOF WITH NUCLEIC ACIDS
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Pub. No.: WO/2017/017294 International Application No.: PCT/ES2016/000081
Publication Date: 02.02.2017 International Filing Date: 21.07.2016
IPC:
C07F 15/00 (2006.01) ,G01N 33/48 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15
Compounds containing elements of the 8th Group of the Periodic System
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
Applicants: UNIVERSIDAD COMPLUTENSE DE MADRID[ES/ES]; Avda. Séneca, 2 28040 Madrid, ES
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CBMSO)[ES/ES]; Calle Serrano, 117 28006 Madrid, ES
Inventors: HERRERO DOMÍNGUEZ, Santiago; ES
JIMENEZ APARICIO, Reyes; ES
MARTÍNEZ SALAS, María Encarnación; ES
LOZANO CUBO, Gloria María; ES
Agent: PONS ARIÑO, Angel; Gta, de Rubén Darío, n° 4 28010 Madrid, ES
Priority Data:
P20150055024.07.2015ES
Title (EN) DIRUTHENIUM COMPOUNDS WITH OPEN-PADDLEWHEEL STRUCTURE AND THE INTERACTION THEREOF WITH NUCLEIC ACIDS
(FR) COMPOSÉS DE DIRUTHÉNIUM, À STRUCTURE EN ROUE À AUBES OUVERTE (OPEN PADDLEWHEEL) ET LEUR INTERACTION AVEC LES ACIDES NUCLÉIQUES.
(ES) COMPUESTOS DE DIRRUTENIO CON ESTRUCTURA DE RUEDA DE PALETAS ABIERTA (OPEN-PADDLEWHEEL) Y SU INTERACCIÓN CON ÁCIDOS NUCLEICOS
Abstract:
(EN) The invention relates to diruthenium compounds with an open-paddlewheel structure, to the stabilisation thereof, to the production method thereof, and to methods for using said compounds in the analysis of the secondary and tertiary structure of RNA, particularly in the determination of intersections between helices or the transition between helices and loops. The invention also relates to a kit containing diruthenium compounds with an open-paddlewheel structure and to the appropriate means for using same in the analysis of the structure of RNA.
(FR) L'invention concerne des composés de diruthénium à structure en roue à aubes ouverte (open paddlewheel), leur stabilisation, leur procédé de préparation, et des procédés d'utilisation de ces composés pour l'analyse de la structure secondaire et tertiaire de l'ARN, en particulier pour la détermination des intersections entre hélices ou de la transition entre hélices et boucles. L'invention concerne également un kit contenant des composés de diruthénium à structure en roue à aubes ouverte (open-paddlewheel) et le matériel approprié pour les utiliser pour l'analyse de la structure de l'ARN.
(ES) La invención se refiere a compuestos de dirrutenio con estructura de rueda de paletas abierta (open-paddiewheel), su estabilización, su método de elaboración y métodos para utilizarlos en el análisis de la estructura secundaria y terciaria del ARN, particularmente en la determinación de las intersecciones entre hélices o en la transición entre hélices y bucles. La invención también se refiere a un kit que contiene compuestos de dirrutenio con estructura de rueda de paletas abierta (open-paddiewheel) y los medios adecuados para utilizarlos en el análisis de la estructura de! ARN.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Spanish (ES)
Filing Language: Spanish (ES)