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1. (WO2017017163) A METHOD FOR CALIBRATING A DIFFUSION IMAGING SEQUENCE DURING A DIFFUSION MRI EXPERIMENT

Pub. No.:    WO/2017/017163    International Application No.:    PCT/EP2016/067964
Publication Date: Fri Feb 03 00:59:59 CET 2017 International Filing Date: Thu Jul 28 01:59:59 CEST 2016
IPC: G01R 33/563
G01R 33/58
Applicants: AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE
Inventors: KRZYZAK, Artur
Title: A METHOD FOR CALIBRATING A DIFFUSION IMAGING SEQUENCE DURING A DIFFUSION MRI EXPERIMENT
Abstract:
A method for calibrating a diffusion imaging sequence during a DMRI (Diffusion Magnetic Resonance Imaging) experiment performed in an MR (Magnetic Resonance) tomograph, wherein the experiment comprises calculating diffusion coefficients and/or diffusion tensor coefficients on the basis of a spatial distribution of a b matrix, the method for calibrating comprising the following steps: within the field of influence of an RF (Radio Frequency) coil in an examined space of the MR tomograph: providing (201) an anisotropic diffusion phantom (101) with known values of diffusion tensor, the anisotropic diffusion phantom (101) having diffusion limited therein in at least one direction along a first axis of the principal axes of the anisotropic diffusion phantom (101); placing the anisotropic diffusion phantom (101) sequentially in a selected location within the examined space in three different positioning arrangements orthogonal with respect to each other; and placing an isotropic diffusion phantom (102) having a known diffusion tensor in said selected location; for each positioning arrangement of the anisotropic diffusion phantom (101) and the isotropic diffusion phantom (102), measuring (202, 205) MR signals; determining (203, 206) the values of the b matrix, based on the measured MR signals, for each voxel of a volume comprised inside both the volume of the anisotropic diffusion phantom (101) and the volume of the isotropic diffusion phantom (102); and providing (207) the determined spatial distribution of the b matrix as a calibration result for the DMRI sequence for the particular MR tomograph.