Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Saturday 31.10.2020 at 7:00 AM CET
Settings

Settings

Goto Application

1. WO2017017116 - NOVEL ADAMANTANE AND MEMANTINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS

Publication Number WO/2017/017116
Publication Date 02.02.2017
International Application No. PCT/EP2016/067846
International Filing Date 26.07.2016
IPC
C07C 211/62 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
62Quaternary ammonium compounds
C07C 211/63 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
62Quaternary ammonium compounds
63having quaternised nitrogen atoms bound to acyclic carbon atoms
CPC
A61P 9/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
C07C 211/62
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
62Quaternary ammonium compounds
C07C 211/63
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
62Quaternary ammonium compounds
63having quaternised nitrogen atoms bound to acyclic carbon atoms
C07C 215/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
215Compounds containing amino and hydroxy groups bound to the same carbon skeleton
02having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
04the carbon skeleton being saturated
06and acyclic
08with only one hydroxy group and one amino group bound to the carbon skeleton
C07C 251/38
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
251Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
32Oximes
34with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
36with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
38to carbon atoms of a saturated carbon skeleton
C07C 2601/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
2601Systems containing only non-condensed rings
02with a three-membered ring
Applicants
  • INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) [FR]/[FR]
  • ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR]/[FR]
  • UNIVERSITÉ PARIS-SUD [FR]/[FR]
Inventors
  • HUMBERT, Marc
  • COHEN-KAMINSKY, Sylvia
  • DUMAS, Sébastien
  • BRU-MERCIER, Gilles
  • ALAMI, Mouad
  • BRION, Jean-Daniel
  • MESSAOUDI, Samir
  • GALVANI, Gilles
Agents
  • CABINET NONY
Priority Data
EP1530622828.07.2015EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL ADAMANTANE AND MEMANTINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS
(FR) NOUVEAUX DÉRIVÉS ADAMANTANE ET MÉMANTINE UTILISÉS COMME ANTAGONISTES PÉRIPHÉRIQUES DES RÉCEPTEUR NMDA
Abstract
(EN)
The present invention relates to cationic compounds of formula (I) for use as peripheral NMDA receptor antagonists.
(FR)
La présente invention concerne des composés cationiques de formule (I) destinés à être utilisés comme antagonistes périphériques des récepteurs NMDA.
Also published as
Latest bibliographic data on file with the International Bureau