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|1. (WO2017017026) NEW POLYPEPTIDE HAVING FERREDOXIN-NADP+ REDUCTASE ACTIVITY, POLYNUCLEOTIDE ENCODING THE SAME AND USES THEREOF|
|Applicants:||INSTITUT NATIONAL DES SCIENCES APPLIQUEES
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
|Title:||NEW POLYPEPTIDE HAVING FERREDOXIN-NADP+ REDUCTASE ACTIVITY, POLYNUCLEOTIDE ENCODING THE SAME AND USES THEREOF|
The present invention relates to a novel polypeptide having the enzymatic activity of reduction of NADP+ using electrons from reduced ferredoxin (Ferredoxin-NADP+ reductase activity), a polynucleotide having a nucleotide sequence encoding such polypeptide and uses thereof. The invention relates to the modulation of the Ferredoxin NADP+ reductase activity in a microorganism by varying the expression level of the polynucleotide coding for such polypeptide. The invention also relates to the production of commodity chemicals, especially ethanol, n- butanol, 1,3-propanediol, 1,2-propanediol, isopropanol and acetone by fermenting microorganisms wherein their Ferredoxin NADP+ reductase activity is modulated.