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1. (WO2017002979) DRUG DELIVERY CARRIER, AND COMPOSITION CONTAINING SAME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/002979 International Application No.: PCT/JP2016/069725
Publication Date: 05.01.2017 International Filing Date: 01.07.2016
IPC:
A61K 47/34 (2017.01) ,A61K 47/10 (2017.01) ,A61K 47/18 (2017.01) ,A61K 47/26 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
34
Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
16
containing nitrogen
18
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
Applicants:
国立大学法人 東京大学 THE UNIVERSITY OF TOKYO [JP/JP]; 東京都文京区本郷七丁目3番1号 3-1, Hongo 7-chome, Bunkyo-Ku, Tokyo 1138654, JP
Inventors:
片岡 一則 KATAOKA, Kazunori; JP
安楽 泰孝 ANRAKU, Yasutaka; JP
堀 真緒 HORI, Mao; JP
Agent:
高島 一 TAKASHIMA, Hajime; JP
Priority Data:
62/187,81602.07.2015US
Title (EN) DRUG DELIVERY CARRIER, AND COMPOSITION CONTAINING SAME
(FR) VECTEUR D'ADMINISTRATION DE MÉDICAMENT, ET COMPOSITION LE CONTENANT
(JA) 薬剤送達用キャリア及びこれを含む組成物
Abstract:
(EN) The present invention provides a carrier comprising a first block copolymer and a second block copolymer, wherein: the first block copolymer is a block copolymer composed of a first non-charged segment and a first complex-forming segment and at least a part of the first block copolymer is modified with a first molecule; the second block copolymer is a block copolymer composed of a second non-charged segment and a second complex-forming segment and at least a part of the second block copolymer is modified with a second molecule; and the first molecule is a GLUT1 ligand and the second molecule is a ligand that is different from the first molecule.
(FR) La présente invention concerne un vecteur comprenant un premier copolymère bloc et un second copolymère bloc, le premier copolymère bloc étant un copolymère bloc composé d'un premier segment non chargé et d'un premier segment de formation de complexe et au moins une partie du premier copolymère bloc étant modifiée par une première molécule; le second copolymère bloc est un copolymère bloc composé d'un second segment non chargé et d'un second segment de formation de complexe et au moins une partie du second copolymère bloc étant modifiée par une seconde molécule; et la première molécule est un ligand GLUT1 et la seconde molécule est un ligand qui est différent de la première molécule.
(JA) 本発明は、第1のブロックコポリマーと第2のブロックコポリマーとを含有するキャリアであって、 前記第1のブロックコポリマーは、第1の非荷電性セグメントと第1の複合体形成セグメントとのブロックコポリマーであり、前記第1のブロックコポリマーの少なくとも一部は、第1の分子で修飾されてなり、 前記第2のブロックコポリマーは、第2の非荷電性セグメントと第2の複合体形成セグメントとのブロックコポリマーであり、前記第2のブロックコポリマーの少なくとも一部は、第2の分子で修飾されてなり、 前記第1の分子はGLUT1リガンドであり、前記第2の分子は、前記第1の分子とは異なるリガンドである、キャリアを提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
EP3318282US20180185281