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1. (WO2016210106) COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2016/210106 International Application No.: PCT/US2016/038983
Publication Date: 29.12.2016 International Filing Date: 23.06.2016
IPC:
A61K 31/69 (2006.01) ,C07F 5/02 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
69
Boron compounds
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
5
Compounds containing elements of the 3rd Group of the Periodic System
02
Boron compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
CALITHERA BIOSCIENCES, INC. [US/US]; 343 Oyster Point Blvd., Suite 200 South San Francisco, CA 94080, US
Inventors:
GROSS, Matthew, I.; US
STEGGERDA, Susanne, M.; US
LI, Weiqun; US
Agent:
HALSTEAD, David, P.; US
Priority Data:
62/183,52423.06.2015US
Title (EN) COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY
(FR) COMPOSITIONS ET PROCÉDÉS D'INHIBITION DE L'ACTIVITÉ DE L'ARGINASE
Abstract:
(EN) The invention relates to methods of treating cancer, with a combination of an arginase inhibitor and a chemotherapeutic agent. The invention further relates to methods of assessing efficacy of a cancer treatment by measuring arginine levels in a tumor.
(FR) L'invention concerne des procédés pour traiter le cancer à l'aide d'une combinaison constituée d'un inhibiteur d'arginase et d'un agent chimiothérapeutique. L'invention concerne également des procédés d'évaluation de l'efficacité d'un traitement du cancer par mesure des taux d'arginine dans une tumeur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)