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1. (WO2016209166) VASCULARIZED TISSUE, SKIN OR MUCOSA EQUIVALENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/209166    International Application No.:    PCT/SG2016/050282
Publication Date: 29.12.2016 International Filing Date: 21.06.2016
IPC:
C12N 5/071 (2010.01), A61L 27/38 (2006.01), A61L 27/60 (2006.01)
Applicants: NATIONAL UNIVERSITY OF SINGAPORE [SG/SG]; 21 Lower Kent Ridge Road Singapore 119077 (SG)
Inventors: CAO, Tong; (SG).
HANDRAL, Harish Kiran; (SG).
GOPU, Sriram; (SG)
Agent: AMICA LAW LLC; 30 Raffles Place #14-01 Chevron House Singapore 048622 (SG)
Priority Data:
1510913.5 22.06.2015 GB
Title (EN) VASCULARIZED TISSUE, SKIN OR MUCOSA EQUIVALENT
(FR) ÉQUIVALENT DE TISSU, DE PEAU OU DE MUQUEUSE VASCULARISÉ
Abstract: front page image
(EN)The disclosure relates to a method for the differentiation of stem cells to endothelial cells, vascular smooth muscle cells, fibroblasts and keratinocytes; their use in the production of a organotypic vascularized skin or mucosa model or composition; a method relating thereto; the use of the model or composition in the testing of pharmaceutical and/or cosmetic agents; and including therapeutic and cosmetic skin compositions developed or tested thereby.
(FR)La présente invention concerne un procédé pour la différenciation de cellules souches en cellules endothéliales, cellules vasculaires de muscle lisse, fibroblastes et kératinocytes ; leur utilisation dans la production d'un modèle ou d'une composition organotypique de peau ou de muqueuse vascularisée ; un procédé s'y rapportant ; l'utilisation du modèle ou de la composition dans le test d'agents pharmaceutiques et/ou cosmétiques ; et comprenant des compositions thérapeutiques et cosmétiques pour la peau développées ou testées par ce moyen.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)