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1. (WO2016193994) AMORPHOUS SELEXIPAG AND PROCESS FOR PREPARATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/193994 International Application No.: PCT/IN2016/000138
Publication Date: 08.12.2016 International Filing Date: 27.05.2016
IPC:
C07D 241/20 (2006.01) ,A61K 31/495 (2006.01) ,A61P 9/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
241
Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
02
not condensed with other rings
10
having three double bonds between ring members or between ring members and non-ring members
14
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
20
Nitrogen atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
12
Antihypertensives
Applicants:
MEGAFINE PHARMA (P) LTD. [IN/IN]; 4th Floor, Sethna 55, Maharshi Karve Road, Marine Lines Mumbai - 400002 Maharashtra, IN
Inventors:
MATHAD, Vijayavitthal Thippannachar; IN
DODDAPPA, Pralhad Anekal; IN
PADAKI, Santhosh Ambadas; IN
KARDILE, Pritesh Bhimraj; IN
GAIKWAD, Bapusaheb Shrihari; IN
SHINDE, Gorakshanath Balasaheb; IN
Agent:
LAXMI, Gururaja Rao; #18, Wing B, Sai-Dwar Apt, Sambhaji Chowk, Untwadi Road Nashik - 422202 Maharashtra, IN
Priority Data:
2086/MUM/201529.05.2015IN
Title (EN) AMORPHOUS SELEXIPAG AND PROCESS FOR PREPARATION THEREOF
(FR) SELEXIPAG AMORPHE ET SON PROCÉDÉ DE PRÉPARATION
Abstract:
(EN) The present invention provides amorphous form of Selexipag and process for the preparation thereof. The present invention also provides amorphous co-precipitate of Selexipag with a pharmaceutically acceptable excipient, process for the manufacture of such pharmaceutical composition.
(FR) La présente invention concerne une nouvelle forme amorphe de selexipag et son procédé de préparation. La présente invention concerne également des co-précipité amorphe de selexipag avec un excipient acceptable sur le plan pharmaceutique, et un procédé pour la fabrication d'une telle composition pharmaceutique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)