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1. (WO2016190420) METHOD FOR TREATING OR PREVENTING DIABETIC NEPHROPATHY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2016/190420 International Application No.: PCT/JP2016/065765
Publication Date: 01.12.2016 International Filing Date: 27.05.2016
IPC:
A61K 31/437 (2006.01) ,A61P 3/10 (2006.01) ,A61P 9/12 (2006.01) ,A61P 13/02 (2006.01) ,A61P 13/12 (2006.01) ,A61P 29/00 (2006.01) ,A61P 37/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
12
Antihypertensives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
02
of urine or of the urinary tract, e.g. urine acidifiers
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
12
of the kidneys
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
Applicants:
日本たばこ産業株式会社 JAPAN TOBACCO INC. [JP/JP]; 東京都港区虎ノ門二丁目2番1号 2-1, Toranomon 2-chome, Minato-ku, Tokyo 1058422, JP
Inventors:
福井 健人 FUKUI, Kenji; JP
篠崎 雄一 SHINOZAKI, Yuichi; JP
稲垣 浩二 INAGAKI, Koji; JP
Agent:
高島 一 TAKASHIMA, Hajime; JP
Priority Data:
2015-10920728.05.2015JP
Title (EN) METHOD FOR TREATING OR PREVENTING DIABETIC NEPHROPATHY
(FR) PROCÉDÉ DE TRAITEMENT OU DE PRÉVENTION DE LA NÉPHROPATHIE DIABÉTIQUE
(JA) 糖尿病性腎症を治療又は予防する方法
Abstract:
(EN) Provided are: a method for treating or preventing renal disorder-related diseases such as diabetic nephropathy, said method comprising administering a therapeutically effective amount of 2-({[7-hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl}amino)acetic acid or a pharmaceutically acceptable salt thereof to a mammal; and a novel medicinal use of the aforesaid compound such as a medicinal composition for treating or preventing renal disorder-related diseases, said medicinal composition comprising the aforesaid compound or a pharmaceutically acceptable salt thereof.
(FR) La présente invention concerne : un procédé de traitement ou de prévention de maladies associées à un trouble rénal telles que la néphropathie diabétique, ledit procédé comprenant l'administration d'une quantité thérapeutiquement efficace d’acide 2-({ [7-hydroxy-5-(2-phényléthyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl}amino)acétique ou un sel pharmaceutiquement acceptable de celui-ci à un mammifère ; et une nouvelle utilisation médicinale du composé mentionné ci-dessus, telle qu'une composition médicinale pour le traitement ou la prévention de maladies associées à des troubles rénaux, ladite composition médicinale comprenant le composé mentionné ci-dessus ou un sel pharmaceutiquement acceptable de celui-ci.
(JA) 本発明は、2-({[7-ヒドロキシ-5-(2-フェニルエチル)-[1,2,4]トリアゾロ[1,5-a]ピリジン-8-イル]カルボニル}アミノ)酢酸(2-({[7-Hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl}amino)acetic acid)又はその製薬上許容される塩の治療上有効量を哺乳動物に投与することを含んでなる、糖尿病性腎症等の腎障害関連疾患を治療又は予防する方法、及び前記化合物又はその製薬上許容される塩を含む、腎障害関連疾患の治療又は予防用医薬組成物などの前記化合物の新規医薬用途を提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)