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1. WO2016189109 - POLYOXOMOLYBDATE-BISPHOSPHONATE COMPLEX CONTAINING A HETEROMETALLIC ION DIFFERENT FROM MOLYBDENUM

Publication Number WO/2016/189109
Publication Date 01.12.2016
International Application No. PCT/EP2016/061948
International Filing Date 26.05.2016
IPC
C07F 11/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
11Compounds containing elements of Groups 6 or 16 of the Periodic System
C07F 13/00 2006.01
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
C07F 15/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
C07F 15/02 2006.01
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
02Iron compounds
C07F 19/00 2006.01
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
19Metal compounds according to more than one of main groups C07F1/-C07F17/110
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07F 11/005
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
11Compounds containing elements of Groups 6 or 16 of the Periodic System
005compounds without a metal-carbon linkage
C07F 13/005
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
005Compounds without a metal-carbon linkage
C07F 15/0053
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
0006compounds of the platinum group
0046Ruthenium compounds
0053without a metal-carbon linkage
C07F 15/0093
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07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
0006compounds of the platinum group
0086Platinum compounds
0093without a metal-carbon linkage
C07F 15/025
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
02Iron compounds
025without a metal-carbon linkage
Applicants
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR]/[FR]
  • UNIVERSITE DE VERSAILLES SAINT-QUENTIN EN YVELINES [FR]/[FR]
Inventors
  • DOLBECQ-BASTIN, Anne
  • SAAD, Ali
  • MIALANE, Pierre
  • OLDFIELD, Eric
  • ZHU, Wei
Agents
  • CABINET NONY
Priority Data
15305812.828.05.2015EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) POLYOXOMOLYBDATE-BISPHOSPHONATE COMPLEX CONTAINING A HETEROMETALLIC ION DIFFERENT FROM MOLYBDENUM
(FR) COMPLEXE POLYOXOMOLYBDATE-BISPHOSPHONATE CONTENANT UN ION HÉTÉROMÉTALLIQUE DIFFÉRENT DU MOLYBDÈNE
Abstract
(EN)
The present invention relates to a polyoxomolybdate-bisphosphonate complex containing a bisphosphonate ligand, wherein it further contains a heterometallic ion different from molybdenum, for use in treating cancer. It further relates to novel polyoxomolybdate-bisphosphonate complexes containing a bisphosphonate ligand, wherein it further contains a heterometallic ion different from molybdenum, to their preparation process and pharmaceutical composition containing them.
(FR)
La présente invention concerne un complexe polyoxomolybdate-bisphosphonate contenant un ligand bisphosphonate et un ion hétérométallique différent du molybdène, à utiliser dans le traitement du cancer. La présente invention concerne également de nouveaux complexes polyoxomolybdate-bisphosphonate contenant un ligand bisphosphonate, et un ion hétérométallique différent du molybdène; leur procédé de préparation et une composition pharmaceutique les contenant.
Also published as
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