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1. (WO2016187459) METHOD FOR GENERATING HUMAN DENDRITIC CELLS FOR IMMUNOTHERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/187459    International Application No.:    PCT/US2016/033339
Publication Date: 24.11.2016 International Filing Date: 19.05.2016
IPC:
C12N 5/0784 (2010.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th Floor Oakland, California 94607-5200 (US)
Inventors: SEET, Christopher S.; (US).
CROOKS, Gay Miriam; (US)
Agent: HUNTER, Tom; (US)
Priority Data:
62/164,368 20.05.2015 US
Title (EN) METHOD FOR GENERATING HUMAN DENDRITIC CELLS FOR IMMUNOTHERAPY
(FR) PROCÉDÉ POUR GÉNÉRER DES CELLULES DENDRITIQUES HUMAINES POUR L'IMMUNOTHÉRAPIE
Abstract: front page image
(EN)In various embodiments methods of producing a cell population enriched for CLEC9A+ dendritic cells are provided where the methods involve culturing stem cells and/or progenitor cells in a cell culture comprising culture medium, a notch ligand, stem cell factor (SCF), FLT3 ligand (FLT3L); thrombopoietin (TPO); and IL-3 and/or GMCSF.
(FR)Dans divers modes de réalisation, l'invention concerne des procédés de production d'une population de cellules enrichie en cellules dendritiques CLEC9A+, les procédés comprenant la culture de cellules souches et/ou de cellules progénitrices dans une culture cellulaire comprenant un milieu de culture, un ligand notch, un facteur des cellules souches (SCF), un ligand FLT3 (FLT3L), de la thrombopoïétine (TPO) et IL-3 et/ou GMCSF.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)