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1. WO2016187039 - IMPLANTABLE HUB AND SATELLITE SYSTEM FOR NEURAL RECORDING AND STIMULATION

Publication Number WO/2016/187039
Publication Date 24.11.2016
International Application No. PCT/US2016/032457
International Filing Date 13.05.2016
IPC
A61N 1/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
A61N 1/372 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
372Arrangements in connection with the implantation of stimulators
CPC
A61B 5/0484
A61B 5/4836
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
48Other medical applications
4836Diagnosis combined with treatment in closed-loop systems or methods
A61N 1/0534
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
05for implantation or insertion into the body, e.g. heart electrode
0526Head electrodes
0529Electrodes for brain stimulation
0534Electrodes for deep brain stimulation
A61N 1/36064
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation
3605Implantable neurostimulators for stimulating central or peripheral nerve system
3606adapted for a particular treatment
36064Epilepsy
A61N 1/36082
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation
3605Implantable neurostimulators for stimulating central or peripheral nerve system
3606adapted for a particular treatment
36082Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
A61N 1/36139
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation
3605Implantable neurostimulators for stimulating central or peripheral nerve system
36128Control systems
36135using physiological parameters
36139with automatic adjustment
Applicants
  • THE CHARLES STARK DRAPER LABORATORY, INC. [US]/[US]
  • THE GENERAL HOSPITAL CORPORATION [US]/[US]
Inventors
  • WHEELER, Jesse J.
  • PARKS, Philip D.
  • MORAN, James E.
  • HAMILTON, Lei H.
  • MCCONLEY, Marc W.
  • CHIN, Sang
  • WIDGE, Alik S.
  • DOUGHERTY, Darin D.
  • ESKANDAR, Emad N.
  • PERLIN, Gayatri E.
Agents
  • GORDON, Edward A.
Priority Data
62/162,49515.05.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMPLANTABLE HUB AND SATELLITE SYSTEM FOR NEURAL RECORDING AND STIMULATION
(FR) CONCENTRATEUR IMPLANTABLE ET SYSTÈME SATELLITAIRE POUR ENREGISTREMENT ET STIMULATION NEURAUX
Abstract
(EN)
The systems and methods described herein include an external base station with a tethered transceiver, an implanted hub that includes power, telemetry, and processing electronics, and a plurality of implanted satellite that contain reconfigurable front-end electronics for interfacing with electrodes. The system can operate in different modes. In a first mode, called a base boost mode, the external base station is used for closed-loop control of stimulation therapies. In a second, autonomous mode, closed-loop control is performed in the hub without direct influence from the base station. In a third mode, streams of neural data are transmitted to an offline processor for offline analysis.
(FR)
La présente invention concerne des systèmes et des procédés qui comprennent une station de base externe avec un émetteur-récepteur captif, un concentrateur implanté qui comprend une électronique d’alimentation, de télémétrie et de traitement, et une pluralité de satellites implantés qui contiennent une électronique frontale reconfigurable pour interfaçage avec des électrodes. Le système peut fonctionner dans différents modes. Dans un premier mode, appelé mode survolteur de base, la station de base externe est utilisée pour une commande à boucle fermée de thérapies de stimulation. Dans un second mode autonome, une commande en boucle fermée est effectuée dans le moyeu sans influence directe de la station de base. Dans un troisième mode, des flux de données neurales sont transmises à un processeur hors ligne pour analyse hors ligne.
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