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1. (WO2016186360) METHOD FOR DIAGNOSING EARLY ONSET OF ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/186360    International Application No.:    PCT/KR2016/004884
Publication Date: 24.11.2016 International Filing Date: 10.05.2016
IPC:
C12Q 1/68 (2006.01), G01N 33/68 (2006.01)
Applicants: ANT LABS INC. [KR/KR]; (Yeongeon-dong, Jeil Bldg) 901-ho, 202, Yulgok-ro, Jongno-gu Seoul 03127 (KR)
Inventors: LEE, Sang Kun; (KR).
KIM, Man Ho; (KR).
CHU, Kon; (KR).
JUNG, Keun Hwa; (KR).
LEE, Soon Tae; (KR).
MOON, Jang Sup; (KR)
Agent: DAHAI INTERNATIONAL PATENT & LAW FIRM; (Samseong-dong, Apple Tree Tower) 15th Floor, 443, Teheran-ro, Gangnam-gu, Seoul 06158 (KR)
Priority Data:
10-2015-0068690 18.05.2015 KR
Title (EN) METHOD FOR DIAGNOSING EARLY ONSET OF ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT
(FR) PROCÉDÉ DE DIAGNOSTIC DE L'APPARITION PRÉCOCE DE LA MALADIE D'ALZHEIMER OU D'UN TROUBLE COGNITIF LÉGER
(KO) 초기 알츠하이머 병 또는 경도 인지 장애 진단 방법
Abstract: front page image
(EN)The present invention relates to a method for diagnosing Alzheimer's disease or mild cognitive impairment. The method for diagnosing Alzheimer's disease or mild cognitive impairment, of the present invention, identifies the expression level of miR-206 in olfactory tissues so as to show a high diagnostic rate of Alzheimer's disease and mild cognitive impairment, enables low cost diagnosis, and has very high biopsy stability, thereby exhibiting a remarkable effect on diagnosing Alzheimer's disease or mild cognitive impairment.
(FR)La présente invention concerne un procédé de diagnostic de la maladie d'Alzheimer ou d'un trouble cognitif léger. Le procédé de diagnostic de la maladie d'Alzheimer ou d'un trouble cognitif léger, de la présente invention, identifie le niveau d'expression de miR-206 dans les tissus olfactifs afin de présenter un niveau de diagnostic élevé de la maladie d'Alzheimer et d'un trouble cognitif léger, permet un diagnostic à faible coût, et présente une stabilité très élevée de la biopsie, faisant preuve de là d'un effet remarquable de diagnostic de la maladie d'Alzheimer ou d'un trouble cognitif léger.
(KO)본 발명은 알츠하이머병 또는 경도 인지 장애 진단 방법에 관한 것이다. 본 발명의 알츠하이머병 또는 경도 인지 장애 진단 방법은 후각 조직의 miR-206의 발현 수준을 확인하여, 알츠하이머병 및 경도 인지 장애 진단에 높은 진단율을 보이며, 적은 비용으로 진단이 가능하며, 조직 검사의 안정성이 매우 높아 알츠하이머병 또는 경도 인지 장애 진단에 현저한 효과를 보인다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)