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Machine translation
1. (WO2016183586) HIGH MOLECULAR WEIGHT, POST-TRANSLATIONALLY MODIFIED PROTEIN BRUSHES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/183586    International Application No.:    PCT/US2016/032757
Publication Date: 17.11.2016 International Filing Date: 16.05.2016
IPC:
A61K 38/17 (2006.01), C07K 1/113 (2006.01), C07K 1/107 (2006.01), C07K 14/47 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massaschusetts Avenue Cambridge, MA 02139 (US)
Inventors: SEIFRIED, Brian, M.; (US).
OLSEN, Bradley, David; (US)
Agent: GORDON, Dana, M.; (US)
Priority Data:
62/161,334 14.05.2015 US
Title (EN) HIGH MOLECULAR WEIGHT, POST-TRANSLATIONALLY MODIFIED PROTEIN BRUSHES
(FR) BROSSES DE PROTÉINES MODIFIÉES APRÈS TRANSLATION ET DE POIDS MOLÉCULAIRE ÉLEVÉ
Abstract: front page image
(EN)Disclosed are protein brushes that mimic mucin in physical and functional characteristics. The protein brushes have a variable number of tandem repeats similar to natural mucin and are modified at a number of their tyrosine residues to introduce brush substituents that mimic the hydrogel nature of mucin.
(FR)L'invention concerne des brosses de protéines qui imitent les caractéristiques physiques et fonctionnelles de la mucine. Les brosses de protéines présentent un nombre variable d'unités de répétition en tandem similaires à la mucine naturelle et sont modifiées au niveau d'un certain nombre de leurs résidus tyrosine pour introduire des substituants de brosses qui imitent la nature hydrogel de la mucine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)