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1. (WO2016183278) HETEROARYL COMPOUNDS FOR KINASE INHIBITION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2016/183278    International Application No.:    PCT/US2016/031996
Publication Date: 17.11.2016 International Filing Date: 12.05.2016
IPC:
C07D 209/04 (2006.01), C07D 209/56 (2006.01), C07D 401/00 (2006.01), C07D 403/12 (2006.01), C07D 471/04 (2006.01)
Applicants: ARIAD PHARMACEUTICALS, INC. [US/US]; 26 Landsdowne Street Cambridge, MA 02139 (US)
Inventors: ZHOU, Tianjun; (US).
YOUNGSAYE, Willmen, W.; (US).
SHAKESPEARE, William, C.; (US).
ISHCHENKO, Alexey, V.; (US).
HUANG, Wei-sheng; (US).
DALGARNO, David, C.; (US)
Agent: YANG, Lucy X.; (US)
Priority Data:
62/160,989 13.05.2015 US
Title (EN) HETEROARYL COMPOUNDS FOR KINASE INHIBITION
(FR) COMPOSÉS HÉTÉROARYLE D'INHIBITION DE LA KINASE
Abstract: front page image
(EN)Compounds and pharmaceutical compositions that modulate kinase activity, including mutant EGFR and mutant HER2 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including mutant EGFRand mutant HER2 activity, are described herein.
(FR)L'invention concerne des composés et des compositions pharmaceutiques qui modulent l'activité de la kinase, y compris l'activité kinase de l'EGFR mutant et l'activité kinase du HER2 mutant. Elle concerne des composés, des compositions pharmaceutiques et des méthodes de traitement de maladies et de troubles associés à l'activité de la kinase, y compris l'activité kinase de l'EGFR mutant et l'activité kinase du HER2 mutant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)